Cargando…
Comparative mRNA Expression of eEF1A Isoforms and a PI3K/Akt/mTOR Pathway in a Cellular Model of Parkinson's Disease
The PI3K/Akt/mTOR pathway is one of dysregulated pathways in Parkinson's disease (PD). Previous studies in nonneuronal cells showed that Akt regulation can be increased by eukaryotic protein elongation factor 1 alpha 2 (eEF1A2). eEF1A2 is proposed to contribute protection against apoptotic deat...
Autores principales: | Khwanraj, Kawinthra, Madlah, Suriyat, Grataitong, Khwanthana, Dharmasaroja, Permphan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769776/ https://www.ncbi.nlm.nih.gov/pubmed/26981313 http://dx.doi.org/10.1155/2016/8716016 |
Ejemplares similares
-
Neuroblastoma Cell Death Induced by eEF1A2 Knockdown Is Possibly Mediated by the Inhibition of Akt and mTOR Phosphorylation
por: Khwanraj, Kawinthra, et al.
Publicado: (2021) -
eEF1A2 siRNA Suppresses MPP(+)-Induced Activation of Akt and mTOR and Potentiates Caspase-3 Activation in a Parkinson's Disease Model
por: Khwanraj, Kawinthra, et al.
Publicado: (2023) -
Differential Expression of Tyrosine Hydroxylase Protein and Apoptosis-Related Genes in Differentiated and Undifferentiated SH-SY5Y Neuroblastoma Cells Treated with MPP(+)
por: Khwanraj, Kawinthra, et al.
Publicado: (2015) -
Evaluation of the Combination of Metformin and Rapamycin in an MPP(+)-Treated SH-SY5Y Model of Parkinson's Disease
por: Norradee, Chureerat, et al.
Publicado: (2023) -
Downregulation of eEF1A/EFT3-4 Enhances Dopaminergic Neurodegeneration After 6-OHDA Exposure in C. elegans Model
por: Chalorak, Pawanrat, et al.
Publicado: (2020)