Rapamycin up-regulates triglycerides in hepatocytes by down-regulating Prox1

BACKGROUND: Although the prolonged use of rapamycin may cause unwanted side effects such as hyperlipidemia, the underlying mechanism remains unknown. Prox1 is a transcription factor responsible for the development of several tissues including lymphatics and liver. There is growing evidences that Pro...

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Detalles Bibliográficos
Autores principales: Kwon, Sora, Jeon, Ji-Sook, Kim, Su Bin, Hong, Young-Kwon, Ahn, Curie, Sung, Jung-Suk, Choi, Inho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769820/
https://www.ncbi.nlm.nih.gov/pubmed/26922671
http://dx.doi.org/10.1186/s12944-016-0211-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769820/
https://www.ncbi.nlm.nih.gov/pubmed/26922671
http://dx.doi.org/10.1186/s12944-016-0211-x

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