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Rapamycin up-regulates triglycerides in hepatocytes by down-regulating Prox1
BACKGROUND: Although the prolonged use of rapamycin may cause unwanted side effects such as hyperlipidemia, the underlying mechanism remains unknown. Prox1 is a transcription factor responsible for the development of several tissues including lymphatics and liver. There is growing evidences that Pro...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769820/ https://www.ncbi.nlm.nih.gov/pubmed/26922671 http://dx.doi.org/10.1186/s12944-016-0211-x |