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Flavokawain B induced cytotoxicity in two breast cancer cell lines, MCF-7 and MDA-MB231 and inhibited the metastatic potential of MDA-MB231 via the regulation of several tyrosine kinases In vitro

BACKGROUND: The kava-kava plant (Piper methysticum) is traditionally consumed by the pacific islanders and has been linked to be involved in several biological activities. Flavokawain B is a unique chalcone, which can be found in the roots of the kava-kava plant. In this study, the operational mecha...

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Detalles Bibliográficos
Autores principales: Abu, Nadiah, Akhtar, M. Nadeem, Yeap, Swee Keong, Lim, Kian Lam, Ho, Wan Yong, Abdullah, Mohd Puad, Ho, Chai Ling, Omar, Abdul Rahman, Ismail, Jamil, Alitheen, Noorjahan Banu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769841/
https://www.ncbi.nlm.nih.gov/pubmed/26922065
http://dx.doi.org/10.1186/s12906-016-1046-8