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Structures of EccB(1) and EccD(1) from the core complex of the mycobacterial ESX-1 type VII secretion system

BACKGROUND: The ESX-1 type VII secretion system is an important determinant of virulence in pathogenic mycobacteria, including Mycobacterium tuberculosis. This complicated molecular machine secretes folded proteins through the mycobacterial cell envelope to subvert the host immune response. Despite...

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Detalles Bibliográficos
Autores principales: Wagner, Jonathan M., Chan, Sum, Evans, Timothy J., Kahng, Sara, Kim, Jennifer, Arbing, Mark A., Eisenberg, David, Korotkov, Konstantin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769845/
https://www.ncbi.nlm.nih.gov/pubmed/26922638
http://dx.doi.org/10.1186/s12900-016-0056-6