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Structures of EccB(1) and EccD(1) from the core complex of the mycobacterial ESX-1 type VII secretion system
BACKGROUND: The ESX-1 type VII secretion system is an important determinant of virulence in pathogenic mycobacteria, including Mycobacterium tuberculosis. This complicated molecular machine secretes folded proteins through the mycobacterial cell envelope to subvert the host immune response. Despite...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769845/ https://www.ncbi.nlm.nih.gov/pubmed/26922638 http://dx.doi.org/10.1186/s12900-016-0056-6 |