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Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses

BACKGROUND: Asthma is strongly associated with allergic sensitization, but the mechanisms that determine why only a subset of atopics develop asthma are not well understood. The aim of this study was to test the hypothesis that variations in allergen-driven CD4 T cell responses are associated with s...

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Detalles Bibliográficos
Autores principales: Troy, Niamh M., Hollams, Elysia M., Holt, Patrick G., Bosco, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769846/
https://www.ncbi.nlm.nih.gov/pubmed/26922672
http://dx.doi.org/10.1186/s12920-016-0171-z