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Neurons in Vulnerable Regions of the Alzheimer’s Disease Brain Display Reduced ATM Signaling123
Ataxia telangiectasia (A-T) is a multisystemic disease caused by mutations in the ATM (A-T mutated) gene. It strikes before 5 years of age and leads to dysfunctions in many tissues, including the CNS, where it leads to neurodegeneration, primarily in cerebellum. Alzheimer’s disease (AD), by contrast...
Autores principales: | Shen, Xuting, Chen, Jianmin, Li, Jiali, Kofler, Julia, Herrup, Karl |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770009/ https://www.ncbi.nlm.nih.gov/pubmed/27022623 http://dx.doi.org/10.1523/ENEURO.0124-15.2016 |
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