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T Cells and Gene Regulation: The Switching On and Turning Up of Genes after T Cell Receptor Stimulation in CD8 T Cells

Signaling downstream of the T cell receptor (TCR) is directly regulated by the dose and affinity of peptide antigen. The strength of TCR signaling drives a multitude of T cell functions from development to differentiation. CD8 T cells differentiate into a diverse pool of effector and memory cells af...

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Detalles Bibliográficos
Autores principales: Conley, James M., Gallagher, Michael P., Berg, Leslie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770016/
https://www.ncbi.nlm.nih.gov/pubmed/26973653
http://dx.doi.org/10.3389/fimmu.2016.00076