Cargando…

T Cells and Gene Regulation: The Switching On and Turning Up of Genes after T Cell Receptor Stimulation in CD8 T Cells

Signaling downstream of the T cell receptor (TCR) is directly regulated by the dose and affinity of peptide antigen. The strength of TCR signaling drives a multitude of T cell functions from development to differentiation. CD8 T cells differentiate into a diverse pool of effector and memory cells af...

Descripción completa

Detalles Bibliográficos
Autores principales:	Conley, James M., Gallagher, Michael P., Berg, Leslie J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770016/ https://www.ncbi.nlm.nih.gov/pubmed/26973653 http://dx.doi.org/10.3389/fimmu.2016.00076

Ejemplares similares

Metabolic Adaptation of Human CD4(+) and CD8(+) T-Cells to T-Cell Receptor-Mediated Stimulation
por: Jones, Nicholas, et al.
Publicado: (2017)

Heritable Gene Regulation in the CD4:CD8 T Cell Lineage Choice
por: Issuree, Priya D. A., et al.
Publicado: (2017)

Porcine NK Cells Stimulate Proliferation of Pseudorabies Virus-Experienced CD8(+) and CD4(+)CD8(+) T Cells
por: De Pelsmaeker, Steffi, et al.
Publicado: (2019)

Peptide Antigen Concentration Modulates Digital NFAT1 Activation in Primary Mouse Naive CD8(+) T Cells as Measured by Flow Cytometry of Isolated Cell Nuclei
por: Gallagher, Michael P., et al.
Publicado: (2018)

Co-Receptor CD8-Mediated Modulation of T-Cell Receptor Functional Sensitivity and Epitope Recognition Degeneracy
por: Szomolay, Barbara, et al.
Publicado: (2013)

Corrigendum: Co-Receptor CD8-Mediated Modulation of T-Cell Receptor Functional Sensitivity and Epitope Recognition Degeneracy
por: Szomolay, Barbara, et al.
Publicado: (2014)

The Significance of Tumor Necrosis Factor Receptor Type II in CD8(+) Regulatory T Cells and CD8(+) Effector T Cells
por: Ye, Lin-Lin, et al.
Publicado: (2018)

Regulation of CD8 T cell by B-cells: A narrative review
por: Van Meerhaeghe, Tess, et al.
Publicado: (2023)

CD8(+) T-Cells as Immune Regulators of Multiple Sclerosis
por: Sinha, Sushmita, et al.
Publicado: (2015)

Estrogen receptor beta signaling in CD8(+) T cells boosts T cell receptor activation and antitumor immunity through a phosphotyrosine switch
por: Yuan, Bin, et al.
Publicado: (2021)

Cognate Antigen Stimulation Generates Potent CD8(+) Inflammatory Effector T Cells
por: Sung, Hsueh-Cheng, et al.
Publicado: (2013)

Gene Expression-Based Identification of Antigen-Responsive CD8(+) T Cells on a Single-Cell Level
por: Fuchs, Yannick F., et al.
Publicado: (2019)

Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells
por: Sorrentino, Claudia, et al.
Publicado: (2019)

Tumor-Infiltrated CD8+ T Cell 10-Gene Signature Related to Clear Cell Renal Cell Carcinoma Prognosis
por: Wang, Jie, et al.
Publicado: (2022)

CD8(+)CD122(+) T-Cells: A Newly Emerging Regulator with Central Memory Cell Phenotypes
por: Liu, Junfeng, et al.
Publicado: (2015)

Regulation of CD8(+) T Cells and Antitumor Immunity by Notch Signaling
por: Tsukumo, Shin-ichi, et al.
Publicado: (2018)

Discipline in Stages: Regulating CD8(+) Resident Memory T Cells
por: Mora-Buch, Rut, et al.
Publicado: (2021)

Gene expression of peripheral blood mononuclear cells and CD8(+) T cells from gilts after PRRSV infection
por: Lagumdzic, Emil, et al.
Publicado: (2023)

Corrigendum: Adenosine A2A Receptor Stimulation Inhibits TCR-Induced Notch1 Activation in CD8+T-Cells
por: Sorrentino, Claudia, et al.
Publicado: (2019)

Harnessing the Induction of CD8(+) T-Cell Responses Through Metabolic Regulation by Pathogen-Recognition-Receptor Triggering in Antigen Presenting Cells
por: Nicoli, Francesco, et al.
Publicado: (2018)

Time and Antigen-Stimulation History Influence Memory CD8 T Cell Bystander Responses
por: Martin, Matthew D., et al.
Publicado: (2017)

Anti-tumor memory CD4 and CD8 T-cells quantified by bulk T-cell receptor (TCR) clonal analysis
por: Gao, Yanhua, et al.
Publicado: (2023)

Turning Up the Heat: Local Temperature Control During in vivo Imaging of Immune Cells
por: Ahl, David, et al.
Publicado: (2019)

Epigenetic Maintenance of Acquired Gene Expression Programs during Memory CD8 T Cell Homeostasis
por: Abdelsamed, Hossam A., et al.
Publicado: (2018)

Inhibitory Molecules PD-1, CD73 and CD39 Are Expressed by CD8(+) T Cells in a Tissue-Dependent Manner and Can Inhibit T Cell Responses to Stimulation
por: Smith, Corinne J., et al.
Publicado: (2021)

Autophagy is a critical regulator of memory CD8(+) T cell formation
por: Puleston, Daniel J, et al.
Publicado: (2014)

Transcriptional and Epigenetic Regulation of Effector and Memory CD8 T Cell Differentiation
por: Chen, Yao, et al.
Publicado: (2018)

EZH2 as a Regulator of CD8+ T Cell Fate and Function
por: Stairiker, Christopher J., et al.
Publicado: (2020)

Mixing Signals: Molecular Turn Ons and Turn Offs for Innate γδ T-Cells
por: Bekiaris, Vasileios, et al.
Publicado: (2014)

Defining Memory CD8 T Cell
por: Martin, Matthew D., et al.
Publicado: (2018)

CD8(+) T Cell Exhaustion in Cancer
por: Dolina, Joseph S., et al.
Publicado: (2021)

Expression of the Inhibitory Receptor TIGIT Is Up-Regulated Specifically on NK Cells With CD226 Activating Receptor From HIV-Infected Individuals
por: Yin, Xiaowan, et al.
Publicado: (2018)

Effect of CpG Depletion of Vector Genome on CD8(+) T Cell Responses in AAV Gene Therapy
por: Bertolini, Thais B., et al.
Publicado: (2021)

Differentiation of Memory CD8 T Cells Unravel Gene Expression Pattern Common to Effector and Memory Precursors
por: Neitzke-Montinelli, Vanessa, et al.
Publicado: (2022)

A CD8(+) T cell-associated immune gene panel for prediction of the prognosis and immunotherapeutic effect of melanoma
por: Sun, Shanwen, et al.
Publicado: (2022)

Allotransplantation Is Associated With Exacerbation of CD8 T-Cell Senescence: The Particular Place of the Innate CD8 T-Cell Component
por: Daniel, Lauren, et al.
Publicado: (2021)

T Cell Receptor–Major Histocompatibility Complex Interaction Strength Defines Trafficking and CD103(+) Memory Status of CD8 T Cells in the Brain
por: Sanecka, Anna, et al.
Publicado: (2018)

The CXC Chemokine Receptor 3 Inhibits Autoimmune Cholangitis via CD8(+) T Cells but Promotes Colitis via CD4(+) T Cells
por: Liu, Qing-Zhi, et al.
Publicado: (2018)

Cytotoxic Activity and Memory T Cell Subset Distribution of in vitro-Stimulated CD8(+) T Cells Specific for HER2/neu Epitopes
por: Kuznetsova, Maria, et al.
Publicado: (2019)

Human Hepatic CD56(bright) NK Cells Display a Tissue-Resident Transcriptional Profile and Enhanced Ability to Kill Allogenic CD8(+) T Cells
por: Jameson, Gráinne, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t58fb3hi6p6j1t068m8975liaj