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Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability

Cytosine can undergo modifications, forming 5-methylcytosine (5-mC) and its oxidized products 5-hydroxymethylcytosine (5-hmC), 5-formylcytosine (5-fC) and 5-carboxylcytosine (5-caC). Despite their importance as epigenetic markers and as central players in cellular processes, it is not well understoo...

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Detalles Bibliográficos
Autores principales: Ngo, Thuy T. M., Yoo, Jejoong, Dai, Qing, Zhang, Qiucen, He, Chuan, Aksimentiev, Aleksei, Ha, Taekjip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770088/
https://www.ncbi.nlm.nih.gov/pubmed/26905257
http://dx.doi.org/10.1038/ncomms10813