Cargando…

Autoregulation of topoisomerase I expression by supercoiling sensitive transcription

The opposing catalytic activities of topoisomerase I (TopoI/relaxase) and DNA gyrase (supercoiling enzyme) ensure homeostatic maintenance of bacterial chromosome supercoiling. Earlier studies in Escherichia coli suggested that the alteration in DNA supercoiling affects the DNA gyrase and TopoI expre...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahmed, Wareed, Menon, Shruti, D. N. B. Karthik, Pullela V., Nagaraja, Valakunja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770202/
https://www.ncbi.nlm.nih.gov/pubmed/26496944
http://dx.doi.org/10.1093/nar/gkv1088