Cargando…

DNA deletion as a mechanism for developmentally programmed centromere loss

A hallmark of active centromeres is the presence of the histone H3 variant CenH3 in the centromeric chromatin, which ensures faithful genome distribution at each cell division. A functional centromere can be inactivated, but the molecular mechanisms underlying the process of centromere inactivation...

Descripción completa

Detalles Bibliográficos
Autores principales: Lhuillier-Akakpo, Maoussi, Guérin, Frédéric, Frapporti, Andrea, Duharcourt, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770206/
https://www.ncbi.nlm.nih.gov/pubmed/26503246
http://dx.doi.org/10.1093/nar/gkv1110