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A novel conceptual approach to read-filtering in high-throughput amplicon sequencing studies

Adequate read filtering is critical when processing high-throughput data in marker-gene-based studies. Sequencing errors can cause the mis-clustering of otherwise similar reads, artificially increasing the number of retrieved Operational Taxonomic Units (OTUs) and therefore leading to the overestima...

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Detalles Bibliográficos
Autores principales: Puente-Sánchez, Fernando, Aguirre, Jacobo, Parro, Víctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770208/
https://www.ncbi.nlm.nih.gov/pubmed/26553806
http://dx.doi.org/10.1093/nar/gkv1113