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Evolution of disorder in Mediator complex and its functional relevance

Mediator, an important component of eukaryotic transcriptional machinery, is a huge multisubunit complex. Though the complex is known to be conserved across all the eukaryotic kingdoms, the evolutionary topology of its subunits has never been studied. In this study, we profiled disorder in the Media...

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Detalles Bibliográficos
Autores principales: Nagulapalli, Malini, Maji, Sourobh, Dwivedi, Nidhi, Dahiya, Pradeep, Thakur, Jitendra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770211/
https://www.ncbi.nlm.nih.gov/pubmed/26590257
http://dx.doi.org/10.1093/nar/gkv1135