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Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex
Nonsense-mediated mRNA decay (NMD) is an mRNA degradation pathway that regulates gene expression and mRNA quality. A complex network of macromolecular interactions regulates NMD initiation, which is only partially understood. According to prevailing models, NMD begins by the assembly of the SURF (SM...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770235/ https://www.ncbi.nlm.nih.gov/pubmed/26740584 http://dx.doi.org/10.1093/nar/gkv1527 |