Mechanism and regulation of the nonsense-mediated decay pathway

The Nonsense-mediated mRNA decay (NMD) pathway selectively degrades mRNAs harboring premature termination codons (PTCs) but also regulates the abundance of a large number of cellular RNAs. The central role of NMD in the control of gene expression requires the existence of buffering mechanisms that t...

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Detalles Bibliográficos
Autores principales: Hug, Nele, Longman, Dasa, Cáceres, Javier F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Survey and Summary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770240/
https://www.ncbi.nlm.nih.gov/pubmed/26773057
http://dx.doi.org/10.1093/nar/gkw010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770240/
https://www.ncbi.nlm.nih.gov/pubmed/26773057
http://dx.doi.org/10.1093/nar/gkw010

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