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New players in heterochromatin silencing: histone variant H3.3 and the ATRX/DAXX chaperone

A number of studies have demonstrated that various components of the ATRX/DAXX/Histone H3.3 complex are important for heterochromatin silencing at multiple genomic regions. We provide an overview of the individual components (ATRX, DAXX and/or H3.3) tested in each study and propose a model where the...

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Detalles Bibliográficos
Autores principales: Voon, Hsiao P.J., Wong, Lee H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770241/
https://www.ncbi.nlm.nih.gov/pubmed/26773061
http://dx.doi.org/10.1093/nar/gkw012