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The K(+)-dependent GTPase Nug1 is implicated in the association of the helicase Dbp10 to the immature peptidyl transferase centre during ribosome maturation

Ribosome synthesis employs a number of energy-consuming enzymes in both eukaryotes and prokaryotes. One such enzyme is the conserved circularly permuted GTPase Nug1 (nucleostemin in human). Nug1 is essential for 60S subunit assembly and nuclear export, but its role and time of action during maturati...

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Detalles Bibliográficos
Autores principales: Manikas, Rizos-Georgios, Thomson, Emma, Thoms, Matthias, Hurt, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770245/
https://www.ncbi.nlm.nih.gov/pubmed/26823502
http://dx.doi.org/10.1093/nar/gkw045