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Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption

OBJECTIVE: The family of acyl-CoA synthetase enzymes (ACSL) activates fatty acids within cells to generate long chain fatty acyl CoA (FACoA). The differing metabolic fates of FACoAs such as incorporation into neutral lipids, phospholipids, and oxidation pathways are differentially regulated by the A...

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Detalles Bibliográficos
Autores principales: Bowman, Thomas A., O'Keeffe, Kayleigh R., D'Aquila, Theresa, Yan, Qing Wu, Griffin, John D., Killion, Elizabeth A., Salter, Deanna M., Mashek, Douglas G., Buhman, Kimberly K., Greenberg, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770262/
https://www.ncbi.nlm.nih.gov/pubmed/26977393
http://dx.doi.org/10.1016/j.molmet.2016.01.001