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Acyl CoA synthetase 5 (ACSL5) ablation in mice increases energy expenditure and insulin sensitivity and delays fat absorption
OBJECTIVE: The family of acyl-CoA synthetase enzymes (ACSL) activates fatty acids within cells to generate long chain fatty acyl CoA (FACoA). The differing metabolic fates of FACoAs such as incorporation into neutral lipids, phospholipids, and oxidation pathways are differentially regulated by the A...
Autores principales: | Bowman, Thomas A., O'Keeffe, Kayleigh R., D'Aquila, Theresa, Yan, Qing Wu, Griffin, John D., Killion, Elizabeth A., Salter, Deanna M., Mashek, Douglas G., Buhman, Kimberly K., Greenberg, Andrew S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770262/ https://www.ncbi.nlm.nih.gov/pubmed/26977393 http://dx.doi.org/10.1016/j.molmet.2016.01.001 |
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