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Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii

Multidrug-resistant Acinetobacter baumannii presents a global medical crisis and polymyxins are used as the last-line therapy. This study aimed to identify metabolic differences between polymyxin-susceptible and polymyxin-resistant A. baumannii using untargeted metabolomics. The metabolome of each A...

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Detalles Bibliográficos
Autores principales: Mahamad Maifiah, Mohd Hafidz, Cheah, Soon-Ee, Johnson, Matthew D., Han, Mei-Ling, Boyce, John D., Thamlikitkul, Visanu, Forrest, Alan, Kaye, Keith S., Hertzog, Paul, Purcell, Anthony W., Song, Jiangning, Velkov, Tony, Creek, Darren J., Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770286/
https://www.ncbi.nlm.nih.gov/pubmed/26924392
http://dx.doi.org/10.1038/srep22287