Autoimmune Responses to Soluble Aggregates of Amyloidogenic Proteins Involved in Neurodegenerative Diseases: Overlapping Aggregation Prone and Autoimmunogenic regions

Why do patients suffering from neurodegenerative diseases generate autoantibodies that selectively bind soluble aggregates of amyloidogenic proteins? Presently, molecular basis of interactions between the soluble aggregates and human immune system is unknown. By analyzing sequences of experimentally...

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Detalles Bibliográficos
Autores principales: Kumar, Sandeep, Thangakani, A. Mary, Nagarajan, R., Singh, Satish K., Velmurugan, D., Gromiha, M. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770294/
https://www.ncbi.nlm.nih.gov/pubmed/26924748
http://dx.doi.org/10.1038/srep22258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770294/
https://www.ncbi.nlm.nih.gov/pubmed/26924748
http://dx.doi.org/10.1038/srep22258

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