Unexpected Reaction Pathway for butyrylcholinesterase-catalyzed inactivation of “hunger hormone” ghrelin

Extensive computational modeling and simulations have been carried out, in the present study, to uncover the fundamental reaction pathway for butyrylcholinesterase (BChE)-catalyzed hydrolysis of ghrelin, demonstrating that the acylation process of BChE-catalyzed hydrolysis of ghrelin follows an unpr...

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Detalles Bibliográficos
Autores principales: Yao, Jianzhuang, Yuan, Yaxia, Zheng, Fang, Zhan, Chang-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770301/
https://www.ncbi.nlm.nih.gov/pubmed/26922910
http://dx.doi.org/10.1038/srep22322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770301/
https://www.ncbi.nlm.nih.gov/pubmed/26922910
http://dx.doi.org/10.1038/srep22322

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