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Myeloid tissue factor does not modulate lung inflammation or permeability during experimental acute lung injury

Tissue factor (TF) is a critical mediator of direct acute lung injury (ALI) with global TF deficiency resulting in increased airspace inflammation, alveolar-capillary permeability, and alveolar hemorrhage after intra-tracheal lipopolysaccharide (LPS). In the lung, TF is expressed diffusely on the lu...

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Detalles Bibliográficos
Autores principales: Shaver, Ciara M., Grove, Brandon S., Clune, Jennifer K., Mackman, Nigel, Ware, Lorraine B., Bastarache, Julie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770302/
https://www.ncbi.nlm.nih.gov/pubmed/26924425
http://dx.doi.org/10.1038/srep22249