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Myeloid tissue factor does not modulate lung inflammation or permeability during experimental acute lung injury
Tissue factor (TF) is a critical mediator of direct acute lung injury (ALI) with global TF deficiency resulting in increased airspace inflammation, alveolar-capillary permeability, and alveolar hemorrhage after intra-tracheal lipopolysaccharide (LPS). In the lung, TF is expressed diffusely on the lu...
Autores principales: | Shaver, Ciara M., Grove, Brandon S., Clune, Jennifer K., Mackman, Nigel, Ware, Lorraine B., Bastarache, Julie A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770302/ https://www.ncbi.nlm.nih.gov/pubmed/26924425 http://dx.doi.org/10.1038/srep22249 |
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