Disease causing mutations in inverted formin 2 regulate its binding to G-actin, F-actin capping protein (CapZ α-1) and profilin 2

Focal segmental glomerulosclerosis (FSGS) is a devastating form of nephrotic syndrome which ultimately leads to end stage renal failure (ESRF). Mutations in inverted formin 2 (INF2), a member of the formin family of actin-regulating proteins, have recently been associated with a familial cause of ne...

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Detalles Bibliográficos
Autores principales: Rollason, Ruth, Wherlock, Matthew, Heath, Jenny A., Heesom, Kate J., Saleem, Moin A., Welsh, Gavin I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2016
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770304/
https://www.ncbi.nlm.nih.gov/pubmed/26764407
http://dx.doi.org/10.1042/BSR20150252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770304/
https://www.ncbi.nlm.nih.gov/pubmed/26764407
http://dx.doi.org/10.1042/BSR20150252

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