Dimethylarginine dimethylaminohydrolase 1 is involved in spinal nociceptive plasticity

Activation of neuronal nitric oxide synthase, and consequent production of nitric oxide (NO), contributes to spinal hyperexcitability and enhanced pain sensation. All NOS isoforms are inhibited endogenously by asymmetric dimethylarginine, which itself is metabolised by dimethylarginine dimethylamino...

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Detalles Bibliográficos
Autores principales: D'Mello, Richard, Sand, Claire A., Pezet, Sophie, Leiper, James M., Gaurilcikaite, Egle, McMahon, Stephen B., Dickenson, Anthony H., Nandi, Manasi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770343/
https://www.ncbi.nlm.nih.gov/pubmed/26098438
http://dx.doi.org/10.1097/j.pain.0000000000000269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770343/
https://www.ncbi.nlm.nih.gov/pubmed/26098438
http://dx.doi.org/10.1097/j.pain.0000000000000269

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