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Positional proteomics reveals differences in N‐terminal proteoform stability

To understand the impact of alternative translation initiation on a proteome, we performed a proteome‐wide study on protein turnover using positional proteomics and ribosome profiling to distinguish between N‐terminal proteoforms of individual genes. By combining pulsed SILAC with N‐terminal COFRADI...

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Detalles Bibliográficos
Autores principales: Gawron, Daria, Ndah, Elvis, Gevaert, Kris, Van Damme, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770386/
https://www.ncbi.nlm.nih.gov/pubmed/26893308
http://dx.doi.org/10.15252/msb.20156662