Antibody-dependent enhancement of dengue virus infection inhibits RLR-mediated Type-I IFN-independent signalling through upregulation of cellular autophagy

Antibody dependent enhancement (ADE) of dengue virus (DENV) infection is identified as the main risk factor of severe Dengue diseases. Through opsonization by subneutralizing or non-neutralizing antibodies, DENV infection suppresses innate cell immunity to facilitate viral replication. However, it i...

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Detalles Bibliográficos
Autores principales: Huang, Xinwei, Yue, Yaofei, Li, Duo, Zhao, Yujiao, Qiu, Lijuan, Chen, Junying, Pan, Yue, Xi, Juemin, Wang, Xiaodan, Sun, Qiangming, Li, Qihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770412/
https://www.ncbi.nlm.nih.gov/pubmed/26923481
http://dx.doi.org/10.1038/srep22303

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770412/
https://www.ncbi.nlm.nih.gov/pubmed/26923481
http://dx.doi.org/10.1038/srep22303

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