CRISPR/cas9, a novel genomic tool to knock down microRNA in vitro and in vivo

MicroRNAs are small and non-coding RNA molecules with the master role in regulation of gene expression at post-transcriptional/translational levels. Many methods have been developed for microRNA loss-of-function study, such as antisense inhibitors and sponges; however, the robustness, specificity, a...

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Detalles Bibliográficos
Autores principales: Chang, Hong, Yi, Bin, Ma, Ruixia, Zhang, Xiaoguo, Zhao, Hongyou, Xi, Yaguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770416/
https://www.ncbi.nlm.nih.gov/pubmed/26924382
http://dx.doi.org/10.1038/srep22312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770416/
https://www.ncbi.nlm.nih.gov/pubmed/26924382
http://dx.doi.org/10.1038/srep22312

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