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Knockdown of zebrafish YY1a can downregulate the phosphatidylserine (PS) receptor expression, leading to induce the abnormal brain and heart development

BACKGROUND: Yin Yang 1 (YY1) is a ubiquitously expressed GLI-Kruppel zinc finger-containing transcriptional regulator. YY1 plays a fundamental role in normal biologic processes such as embryogenesis, differentiation, and cellular proliferation. YY1 effects on the genes involved in these processes ar...

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Detalles Bibliográficos
Autores principales: Shiu, Wei-Lun, Huang, Kuan-Rong, Hung, Jo-Chi, Wu, Jen-Leih, Hong, Jiann-Ruey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770675/
https://www.ncbi.nlm.nih.gov/pubmed/26924789
http://dx.doi.org/10.1186/s12929-016-0248-1