LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation

The actin and microtubule cytoskeletons are critically important for cancer cell proliferation, and drugs that target microtubules are widely-used cancer therapies. However, their utility is compromised by toxicities due to dose and exposure. To overcome these issues, we characterized how inhibition...

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Detalles Bibliográficos
Autores principales: Mardilovich, Katerina, Baugh, Mark, Crighton, Diane, Kowalczyk, Dominika, Gabrielsen, Mads, Munro, June, Croft, Daniel R., Lourenco, Filipe, James, Daniel, Kalna, Gabriella, McGarry, Lynn, Rath, Oliver, Shanks, Emma, Garnett, Mathew J., McDermott, Ultan, Brookfield, Joanna, Charles, Mark, Hammonds, Tim, Olson, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770715/
https://www.ncbi.nlm.nih.gov/pubmed/26540348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770715/
https://www.ncbi.nlm.nih.gov/pubmed/26540348

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