Chromosomal instability triggers cell death via local signalling through the innate immune receptor Toll

Chromosomal instability (CIN) is a hallmark of cancer and has been implicated in cancer initiation, progression and the development of resistance to traditional cancer therapy. Here we identify a new property of CIN cells, showing that inducing CIN in proliferating Drosophila larval tissue leads to...

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Detalles Bibliográficos
Autores principales: Liu, Dawei, Shaukat, Zeeshan, Saint, Robert B., Gregory, Stephen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper: Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770720/
https://www.ncbi.nlm.nih.gov/pubmed/26462024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770720/
https://www.ncbi.nlm.nih.gov/pubmed/26462024

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