Cytokeratin-19 positivity is acquired along cancer progression and does not predict cell origin in rat hepatocarcinogenesis

Although the expression of the stem/progenitor cell marker cytokeratin-19 (CK-19) has been associated with the worst clinical prognosis among all HCC subclasses, it is yet unknown whether its presence in HCC is the result of clonal expansion of hepatic progenitor cells (HPCs) or of de-differentiatio...

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Detalles Bibliográficos
Autores principales: Kowalik, Marta Anna, Sulas, Pia, Ledda-Columbano, Giovanna Maria, Giordano, Silvia, Columbano, Amedeo, Perra, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770734/
https://www.ncbi.nlm.nih.gov/pubmed/26452031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770734/
https://www.ncbi.nlm.nih.gov/pubmed/26452031

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