Identification of the β-catenin/JNK/prothymosin-alpha axis as a novel target of sorafenib in hepatocellular carcinoma cells

Sorafenib is a kinase inhibitor used as anticancer drug against various human tumors, including advanced hepatocellular carcinoma (HCC). β-Catenin and prothymosin alpha (PTMA) are overexpressed in HCC and other tumors. Previous studies have shown that PTMA expression modulates the response of HCC ce...

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Detalles Bibliográficos
Autores principales: Lin, Yi-Te, Chao, Chuck C.-K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770752/
https://www.ncbi.nlm.nih.gov/pubmed/26517516

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770752/
https://www.ncbi.nlm.nih.gov/pubmed/26517516

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