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Bladder cancer cells re-educate TAMs through lactate shuttling in the microfluidic cancer microenvironment

BACKGROUND: In the present study, we aimed to investigate the influence of lactate shuttling on the functional polarization and spatial distribution of transitional cell carcinoma of the bladder (TCCB) cells and macrophages. METHODS: We designed a microfluidic coculture chip for real-time integrativ...

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Detalles Bibliográficos
Autores principales: Zhao, Yang, Wang, Degui, Xu, Ting, Liu, Pengfei, Cao, Yanwei, Wang, Yonghua, Yang, Xuecheng, Xu, Xiaodong, Wang, Xinsheng, Niu, Haitao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770766/
https://www.ncbi.nlm.nih.gov/pubmed/26474279