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OX130 Monoclonal Antibody Recognizes Human SIRPβ1 but Cross-Reacts on SIRPα from One Allele

The SIRP family of myeloid-paired receptors are characterized by having both activating and inhibiting members with extracellular regions that are relatively similar. Making good reagents to these receptors is not straightforward, particularly as they are relatively polymorphic. We describe the prod...

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Detalles Bibliográficos
Autores principales: Hatherley, Deborah, Aknin, Marie-Laure, Barclay, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770912/
https://www.ncbi.nlm.nih.gov/pubmed/26871367
http://dx.doi.org/10.1089/mab.2015.0054