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Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription

Acute liver failure, i.e., the fatal deterioration of liver function, is the most common indication that emergency liver transplantation is necessary. Moreover, in the USA, drug-induced liver injury (DILI), including acetaminophen (APAP)-induced hepatotoxicity, is the main cause of acute liver failu...

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Detalles Bibliográficos
Autores principales: PARK, WOO-JAE, KIM, SO-YEON, KIM, YE-RYUNG, PARK, JOO-WON
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771096/
https://www.ncbi.nlm.nih.gov/pubmed/26797017
http://dx.doi.org/10.3892/ijmm.2016.2461