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Three-dimensional polyacrylamide gel-based DNA microarray method effectively identifies UDP-glucuronosyltransferase 1A1 gene polymorphisms for the correct diagnosis of Gilbert's syndrome

Gilbert's syndrome is a mild genetic liver disorder characterized by unconjugated hyperbilirubinemia due to defects in the UDP-glucuronosyltransferase 1A1 (UGT1A1) gene. The T-3279G mutation in the phenobarbital responsive enhancer module (PBREM), the TA-insertion in the TATA box, creating the...

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Detalles Bibliográficos
Autores principales: SONG, JINYUN, SUN, MEI, LI, JIAYAN, ZHOU, DONGRUI, WU, XUPING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771114/
https://www.ncbi.nlm.nih.gov/pubmed/26781906
http://dx.doi.org/10.3892/ijmm.2016.2453