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Evolution of the protease-activated receptor family in vertebrates

Belonging to the G protein-coupled receptor (GPcr) family, the protease-activated receptors (Pars) consist of 4 members, PAR1-4. PARs mediate the activation of cells via thrombin, serine and other proteases. Such protease-triggered signaling events are thought to be critical for hemostasis, thrombos...

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Detalles Bibliográficos
Autores principales: JIN, MIN, YANG, HAI-WEI, TAO, AI-LIN, WEI, JI-FU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771116/
https://www.ncbi.nlm.nih.gov/pubmed/26820116
http://dx.doi.org/10.3892/ijmm.2016.2464