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Increasing the Number of SNP loci does not Necessarily Improve Prediction Power at Least in the Comparison of MTHFR SNP and Haplotypes

BACKGROUND: Rapid advances in genotyping technology have made it possible to easily utilize a large number of genetic markers. According to information theory, an increase in the number of markers provides more information; however, the clinical usefulness does not increase linearly. This study aime...

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Detalles Bibliográficos
Autores principales: Miyaki, Koichi, Takahashi, Yoshimitsu, Song, Yixuan, Zhang, Ling, Muramatsu, Masaaki, Nakayama, Takeo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Epidemiological Association 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771609/
https://www.ncbi.nlm.nih.gov/pubmed/19075497
http://dx.doi.org/10.2188/jea.JE2008022