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Increasing the Number of SNP loci does not Necessarily Improve Prediction Power at Least in the Comparison of MTHFR SNP and Haplotypes
BACKGROUND: Rapid advances in genotyping technology have made it possible to easily utilize a large number of genetic markers. According to information theory, an increase in the number of markers provides more information; however, the clinical usefulness does not increase linearly. This study aime...
Autores principales: | Miyaki, Koichi, Takahashi, Yoshimitsu, Song, Yixuan, Zhang, Ling, Muramatsu, Masaaki, Nakayama, Takeo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japan Epidemiological Association
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771609/ https://www.ncbi.nlm.nih.gov/pubmed/19075497 http://dx.doi.org/10.2188/jea.JE2008022 |
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