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Ethyl pyruvate attenuated coxsackievirus B3-induced acute viral myocarditis by suppression of HMGB1/RAGE/NF-ΚB pathway

Inflammation plays important roles in the pathogenesis of coxsackievirus B3 (CVB3)-induced acute viral myocarditis (AVMC). Ethyl pyruvate (EP) has been shown to be an anti-inflammatory agent. High mobility group box 1 (HMGB1)/receptor for advanced glycation end product (RAGE)/nuclear factor (NF)-ΚB...

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Detalles Bibliográficos
Autores principales: Yu, Ying, Yu, Yong, Liu, Ming, Yu, Peng, Liu, Guijian, Liu, Yuxi, Su, Yangang, Jiang, Hong, Chen, Ruizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771665/
https://www.ncbi.nlm.nih.gov/pubmed/27026909
http://dx.doi.org/10.1186/s40064-016-1857-6