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Effects of cardioactive drugs on human induced pluripotent stem cell derived long QT syndrome cardiomyocytes

Human induced pluripotent stem cells (hiPSC) have enabled a major step forward in pathophysiologic studies of inherited diseases and may also prove to be valuable in in vitro drug testing. Long QT syndrome (LQTS), characterized by prolonged cardiac repolarization and risk of sudden death, may be inh...

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Detalles Bibliográficos
Autores principales: Kuusela, Jukka, Kujala, Ville J., Kiviaho, Anna, Ojala, Marisa, Swan, Heikki, Kontula, Kimmo, Aalto-Setälä, Katriina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771667/
https://www.ncbi.nlm.nih.gov/pubmed/27026928
http://dx.doi.org/10.1186/s40064-016-1889-y