A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells

The inactivation of p53 creates a major challenge for inducing apoptosis in cancer cells. An attractive strategy is to identify and subsequently target the survival signals in p53 defective cancer cells. Here we uncover a RUNX2-mediated survival signal in p53 defective cancer cells. The inhibition o...

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Detalles Bibliográficos
Autores principales: Shin, Min Hwa, He, Yunlong, Marrogi, Eryney, Piperdi, Sajida, Ren, Ling, Khanna, Chand, Gorlick, Richard, Liu, Chengyu, Huang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771715/
https://www.ncbi.nlm.nih.gov/pubmed/26925584
http://dx.doi.org/10.1371/journal.pgen.1005884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771715/
https://www.ncbi.nlm.nih.gov/pubmed/26925584
http://dx.doi.org/10.1371/journal.pgen.1005884

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