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Genome-Wide and Experimental Resolution of Relative Translation Elongation Speed at Individual Gene Level in Human Cells

In the process of translation, ribosomes first assemble on mRNAs (translation initiation) and then translate along the mRNA (elongation) to synthesize proteins. Elongation pausing is deemed highly relevant to co-translational folding of nascent peptides and the functionality of protein products, whi...

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Detalles Bibliográficos
Autores principales: Lian, Xinlei, Guo, Jiahui, Gu, Wei, Cui, Yizhi, Zhong, Jiayong, Jin, Jingjie, He, Qing-Yu, Wang, Tong, Zhang, Gong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771717/
https://www.ncbi.nlm.nih.gov/pubmed/26926465
http://dx.doi.org/10.1371/journal.pgen.1005901