Cargando…
Genome-Wide and Experimental Resolution of Relative Translation Elongation Speed at Individual Gene Level in Human Cells
In the process of translation, ribosomes first assemble on mRNAs (translation initiation) and then translate along the mRNA (elongation) to synthesize proteins. Elongation pausing is deemed highly relevant to co-translational folding of nascent peptides and the functionality of protein products, whi...
Autores principales: | Lian, Xinlei, Guo, Jiahui, Gu, Wei, Cui, Yizhi, Zhong, Jiayong, Jin, Jingjie, He, Qing-Yu, Wang, Tong, Zhang, Gong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771717/ https://www.ncbi.nlm.nih.gov/pubmed/26926465 http://dx.doi.org/10.1371/journal.pgen.1005901 |
Ejemplares similares
-
Translating mRNAs strongly correlate to proteins in a multivariate manner and their translation ratios are phenotype specific
por: Wang, Tong, et al.
Publicado: (2013) -
Generic Algorithm to Predict the Speed of Translational Elongation: Implications for Protein Biogenesis
por: Zhang, Gong, et al.
Publicado: (2009) -
Codon usage and protein length-dependent feedback from translation elongation regulates translation initiation and elongation speed
por: Lyu, Xueliang, et al.
Publicado: (2021) -
Determinants of Translation Elongation Speed and Ribosomal Profiling Biases in Mouse Embryonic Stem Cells
por: Dana, Alexandra, et al.
Publicado: (2012) -
Codon usage regulates protein structure and function by affecting translation elongation speed in Drosophila cells
por: Zhao, Fangzhou, et al.
Publicado: (2017)