Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway

Sustained hypoxic exposure increases ventilatory sensitivity to hypoxia as part of physiological acclimatisation. Oxygen‐sensitive signals are transduced in animal cells by post‐translational hydroxylation of transcription factors termed hypoxia‐inducible factors (HIFs). Mice heterozygous for the pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Hodson, Emma J., Nicholls, Lynn G., Turner, Philip J., Llyr, Ronan, Fielding, James W., Douglas, Gillian, Ratnayaka, Indrika, Robbins, Peter A., Pugh, Christopher W., Buckler, Keith J., Ratcliffe, Peter J., Bishop, Tammie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771794/
https://www.ncbi.nlm.nih.gov/pubmed/26337139
http://dx.doi.org/10.1113/JP271050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771794/
https://www.ncbi.nlm.nih.gov/pubmed/26337139
http://dx.doi.org/10.1113/JP271050

Ejemplares similares