The BBSome Controls Energy Homeostasis by Mediating the Transport of the Leptin Receptor to the Plasma Membrane

Bardet-Biedl syndrome (BBS) is a highly pleiotropic autosomal recessive disorder associated with a wide range of phenotypes including obesity. However, the underlying mechanism remains unclear. Here, we show that neuronal BBSome is a critical determinant of energy balance through its role in the reg...

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Detalles Bibliográficos
Autores principales: Guo, Deng-Fu, Cui, Huxing, Zhang, Qihong, Morgan, Donald A., Thedens, Daniel R., Nishimura, Darryl, Grobe, Justin L., Sheffield, Val C., Rahmouni, Kamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771807/
https://www.ncbi.nlm.nih.gov/pubmed/26926121
http://dx.doi.org/10.1371/journal.pgen.1005890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771807/
https://www.ncbi.nlm.nih.gov/pubmed/26926121
http://dx.doi.org/10.1371/journal.pgen.1005890

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