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Co-culture with intestinal epithelial organoids allows efficient expansion and motility analysis of intraepithelial lymphocytes

BACKGROUND: Intraepithelial lymphocytes (IELs) in the intestine play important roles in the regulation of local immune responses. Although their functions have been studied in a variety of animal experiments, in vitro studies on spatiotemporal behaviors of IELs and their interaction with intestinal...

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Detalles Bibliográficos
Autores principales: Nozaki, Kengo, Mochizuki, Wakana, Matsumoto, Yuka, Matsumoto, Taichi, Fukuda, Masayoshi, Mizutani, Tomohiro, Watanabe, Mamoru, Nakamura, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4771822/
https://www.ncbi.nlm.nih.gov/pubmed/26800996
http://dx.doi.org/10.1007/s00535-016-1170-8